The US and Russia, two world super-powers, and Turkey and Iran, the two regional Islamic powers, are locked into a deadly confrontation with no political issue in sight.
The vice president's staff said Iran policy will top his agenda in meetings with Israeli officials, and will dominate his remarks to the Knesset.
More than 150 guests were able to flee as parts of the building caught fire.
Explosions and heavy gunfire were heard as a 13-hour siege on a luxury hotel in Afghanistan's capital came to an end.
The call came during a visit by the semi-autonomous Kurdistan region's Prime Minister Nechirvan Barzani.
The Syrian-Kurdish YPG militia, supported by the United States but seen as a terrorist organization by Turkey, said it had repulsed the Turkish forces and their allies after fierce clashes.
Pence is the first senior official of the Donald Trump administration to visit the Middle East since Trump's declaration of Jerusalem as the capital of Israel
The Lebanese army rescued six Syrians at a border crossing, one of whom later died in the hospital.
Foreign governments continue to pursue inconsistent policies towards Lebanese leaders, thanks to Hezbollah's participation in the country's government.
A weekly selection of opinions and analyses from the Arab media around the world.
Mike Pence left Washington at the onset of a government shutdown and amid bipartisan calls from Capitol Hill on him to raise growing concern with Sisi over his government’s human rights record.
Direct military action against territory held by Kurdish militia opens a new front in Syria's civil war and sees Ankara confronting Kurds allied to the United States.
Germany wants to punish Iran for its missile program and its meddling in conflicts in other Middle East countries, such as the war in Yemen and Syria.
What does it all mean for Israel?
"Fundamentally, we just don't believe that we have to be the chief donor to every organization around the world."
A Reuters cameraman filmed Turkish artillery at the border village of Sugedigi firing shells on Friday morning into the Afrin region in northwest Syria.
The attacks, which seized control of Android smartphones, allowed the hackers to turn them into victim-monitoring devices and to steal any data from them undetected, researchers said.
"We’re not going to reward bad behavior," said the US envoy to the UN, referring to cut in funding to refugee aid group.
Five Israelis and a Bulgarian were murdered in Hezbollah bomb attack.
UNRWA provides education, health and social welfare to Palestinian refugees in the West Bank, Gaza Strip, Lebanon, Syria and Jordan.